Kazuaki Ohtsubo Selected Research

Enzymes

1/2017	A keratan sulfate disaccharide prevents inflammation and the progression of emphysema in murine models.
1/2011	Hypoxic regulation of glycosylation via the N-acetylglucosamine cycle.

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Kazuaki Ohtsubo Research Topics

Disease

6	Neoplasms (Cancer) 05/2022 - 01/2011
6	Chronic Obstructive Pulmonary Disease (COPD) 01/2017 - 07/2012
4	Emphysema 01/2017 - 05/2012
2	Neoplasm Metastasis (Metastasis) 05/2022 - 01/2011
2	Inflammation (Inflammations) 01/2017 - 04/2012
2	Type 2 Diabetes Mellitus (MODY) 01/2010 - 12/2005
1	Squamous Cell Carcinoma of Head and Neck 01/2021
1	Neurodegenerative Diseases (Neurodegenerative Disease) 04/2016
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 04/2016
1	Alzheimer Disease (Alzheimer's Disease) 04/2016
1	Parkinson Disease (Parkinson's Disease) 04/2016
1	Hepatocellular Carcinoma (Hepatoma) 09/2013
1	Insulinoma 09/2013
1	Disease Progression 07/2012
1	Atherosclerosis 05/2012
1	Chronic Disease (Chronic Diseases) 04/2012
1	Obesity 08/2011
1	Metabolic Diseases (Metabolic Disease) 08/2011
1	Hyperinsulinism (Hyperinsulinemia) 08/2011
1	Hyperglycemia 08/2011
1	Glucose Intolerance 08/2011
1	Hypoxia (Hypoxemia) 01/2011
1	Pancreatic Neoplasms (Pancreatic Cancer) 07/2010
1	Hemorrhage 12/2007
1	Autoimmune Diseases (Autoimmune Disease) 07/2006
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 07/2006

Drug/Important Bio-Agent (IBA)

7	Polysaccharides (Glycans)IBA 01/2017 - 01/2011
3	Matrix Metalloproteinases (MMPs)IBA 01/2017 - 05/2012
3	Pancreatic Elastase (Elastase)IBA 01/2017 - 07/2012
3	SmokeIBA 01/2017 - 05/2012
3	Sialic Acid Binding Immunoglobulin-like LectinsIBA 01/2017 - 02/2013
3	Biomarkers (Surrogate Marker)IBA 07/2014 - 04/2012
2	AntigensIBA 05/2022 - 02/2013
2	Proteins (Proteins, Gene)FDA Link 01/2017 - 02/2013
2	EnzymesIBA 01/2017 - 01/2011
2	LigandsIBA 05/2012 - 12/2007
2	GlycosyltransferasesIBA 08/2011 - 01/2011
2	Insulin (Novolin)FDA Link 08/2011 - 12/2005
2	Glucose (Dextrose)FDA LinkGeneric 01/2011 - 12/2005
2	NucleotidesIBA 01/2011 - 07/2010
2	SugarsIBA 01/2011 - 07/2010
1	EpitopesIBA 05/2022
1	CarbohydratesIBA 05/2022
1	Myosins (Myosin)IBA 01/2021
1	DNA (Deoxyribonucleic Acid)IBA 01/2021
1	CytokinesIBA 01/2017
1	DisaccharidesIBA 01/2017
1	Keratan SulfateIBA 01/2017
1	Peroxidase (Myeloperoxidase)IBA 01/2017
1	Reactive Nitrogen SpeciesIBA 04/2016
1	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2016
1	Interleukin-27 (Interleukin 27)IBA 07/2014
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 12/2013
1	LipopolysaccharidesIBA 12/2013
1	PerforinIBA 12/2013
1	Tissue Inhibitor of Metalloproteinase-1IBA 12/2013
1	Cytidine Monophosphate (CMP)IBA 09/2013
1	AcidsIBA 09/2013
1	Sialic AcidsIBA 09/2013
1	sialosyl-Tn antigenIBA 02/2013
1	Transforming Growth Factors (Transforming Growth Factor)IBA 05/2012
1	oxidized low density lipoproteinIBA 05/2012
1	Lipoproteins (Lipoprotein)IBA 05/2012
1	acetyl-LDLIBA 05/2012
1	Scavenger Receptors (Scavenger Receptor)IBA 05/2012
1	Peptide Hydrolases (Proteases)FDA Link 05/2012
1	Tumor Biomarkers (Tumor Markers)IBA 04/2012
1	Nonesterified Fatty Acids (NEFA)IBA 08/2011
1	AcetylglucosamineIBA 01/2011
1	Guanosine Diphosphate (GDP)IBA 07/2010
1	Uridine Diphosphate (UDP)IBA 07/2010
1	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase (N-acetylglucosaminyltransferase)IBA 01/2010
1	Blood Coagulation Factors (Coagulation Factor)IBA 12/2007
1	SelectinsIBA 12/2007
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 07/2006
1	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 12/2005

Therapy/Procedure

1	Aftercare (After-Treatment) 07/2012